Arsene Wenger’s last trip to Old Trafford as Arsenal manager was ruined after Marouane Fellaini’s last-minute header secured United a 2-1 victory.
Pogba had broken the deadlock for the hosts in the first half, but a Mkhitaryan goal against his former club early in the second half appeared to be enough for Arsenal side to earn a point.
The result leaves the Gunners still sixth in the table and 11 points adrift of fourth-placed Tottenham Hotspur with only three games remaining.
Wenger will at least be hoping that the scene of his first Arsenal defeat is also the scene of his last heading into Thursday’s crucial Europa League semi-final second leg against Atletico Madrid.
Arsenal has now lost 10 away games in a single season for the first time since 1989-90 and that they are guaranteed to end the campaign with their lowest ever points tally under Wenger.